diff --git a/src/frontend/A32/decoder/thumb32.h b/src/frontend/A32/decoder/thumb32.h
index aeac8d18..452466ee 100644
--- a/src/frontend/A32/decoder/thumb32.h
+++ b/src/frontend/A32/decoder/thumb32.h
@@ -238,7 +238,7 @@ std::optional<std::reference_wrapper<const Thumb32Matcher<V>>> DecodeThumb32(u32
         INST(&V::thumb32_SADD16,         "SADD16",                   "111110101001nnnn1111dddd0000mmmm"),
         INST(&V::thumb32_SASX,           "SASX",                     "111110101010nnnn1111dddd0000mmmm"),
         INST(&V::thumb32_SSAX,           "SSAX",                     "111110101110nnnn1111dddd0000mmmm"),
-        //INST(&V::thumb32_SSUB16,         "SSUB16",                   "111110101101----1111----0000----"),
+        INST(&V::thumb32_SSUB16,         "SSUB16",                   "111110101101nnnn1111dddd0000mmmm"),
         //INST(&V::thumb32_SADD8,          "SADD8",                    "111110101000----1111----0000----"),
         //INST(&V::thumb32_SSUB8,          "SSUB8",                    "111110101100----1111----0000----"),
         //INST(&V::thumb32_QADD16,         "QADD16",                   "111110101001----1111----0001----"),
@@ -258,7 +258,7 @@ std::optional<std::reference_wrapper<const Thumb32Matcher<V>>> DecodeThumb32(u32
         INST(&V::thumb32_UADD16,         "UADD16",                   "111110101001nnnn1111dddd0100mmmm"),
         INST(&V::thumb32_UASX,           "UASX",                     "111110101010nnnn1111dddd0100mmmm"),
         INST(&V::thumb32_USAX,           "USAX",                     "111110101110nnnn1111dddd0100mmmm"),
-        //INST(&V::thumb32_USUB16,         "USUB16",                   "111110101101----1111----0100----"),
+        INST(&V::thumb32_USUB16,         "USUB16",                   "111110101101nnnn1111dddd0100mmmm"),
         //INST(&V::thumb32_UADD8,          "UADD8",                    "111110101000----1111----0100----"),
         //INST(&V::thumb32_USUB8,          "USUB8",                    "111110101100----1111----0100----"),
         //INST(&V::thumb32_UQADD16,        "UQADD16",                  "111110101001----1111----0101----"),
diff --git a/src/frontend/A32/translate/impl/thumb32_parallel.cpp b/src/frontend/A32/translate/impl/thumb32_parallel.cpp
index 32fac7dc..3589a137 100644
--- a/src/frontend/A32/translate/impl/thumb32_parallel.cpp
+++ b/src/frontend/A32/translate/impl/thumb32_parallel.cpp
@@ -49,6 +49,20 @@ bool ThumbTranslatorVisitor::thumb32_SSAX(Reg n, Reg d, Reg m) {
     return true;
 }
 
+bool ThumbTranslatorVisitor::thumb32_SSUB16(Reg n, Reg d, Reg m) {
+    if (d == Reg::PC || n == Reg::PC || m == Reg::PC) {
+        return UnpredictableInstruction();
+    }
+
+    const auto reg_m = ir.GetRegister(m);
+    const auto reg_n = ir.GetRegister(n);
+    const auto result = ir.PackedSubS16(reg_n, reg_m);
+
+    ir.SetRegister(d, result.result);
+    ir.SetGEFlags(result.ge);
+    return true;
+}
+
 bool ThumbTranslatorVisitor::thumb32_UADD16(Reg n, Reg d, Reg m) {
     if (d == Reg::PC || n == Reg::PC || m == Reg::PC) {
         return UnpredictableInstruction();
@@ -91,4 +105,18 @@ bool ThumbTranslatorVisitor::thumb32_USAX(Reg n, Reg d, Reg m) {
     return true;
 }
 
+bool ThumbTranslatorVisitor::thumb32_USUB16(Reg n, Reg d, Reg m) {
+    if (d == Reg::PC || n == Reg::PC || m == Reg::PC) {
+        return UnpredictableInstruction();
+    }
+
+    const auto reg_m = ir.GetRegister(m);
+    const auto reg_n = ir.GetRegister(n);
+    const auto result = ir.PackedSubU16(reg_n, reg_m);
+
+    ir.SetRegister(d, result.result);
+    ir.SetGEFlags(result.ge);
+    return true;
+}
+
 } // namespace Dynarmic::A32
diff --git a/src/frontend/A32/translate/impl/translate_thumb.h b/src/frontend/A32/translate/impl/translate_thumb.h
index 54662723..fe8bb751 100644
--- a/src/frontend/A32/translate/impl/translate_thumb.h
+++ b/src/frontend/A32/translate/impl/translate_thumb.h
@@ -132,9 +132,11 @@ struct ThumbTranslatorVisitor final {
     bool thumb32_SADD16(Reg n, Reg d, Reg m);
     bool thumb32_SASX(Reg n, Reg d, Reg m);
     bool thumb32_SSAX(Reg n, Reg d, Reg m);
+    bool thumb32_SSUB16(Reg n, Reg d, Reg m);
     bool thumb32_UADD16(Reg n, Reg d, Reg m);
     bool thumb32_UASX(Reg n, Reg d, Reg m);
     bool thumb32_USAX(Reg n, Reg d, Reg m);
+    bool thumb32_USUB16(Reg n, Reg d, Reg m);
 };
 
 } // namespace Dynarmic::A32
diff --git a/tests/A32/fuzz_thumb.cpp b/tests/A32/fuzz_thumb.cpp
index d239f4b2..e0a5f889 100644
--- a/tests/A32/fuzz_thumb.cpp
+++ b/tests/A32/fuzz_thumb.cpp
@@ -420,12 +420,16 @@ TEST_CASE("Fuzz Thumb32 instructions set", "[JitX64][Thumb][Thumb32]") {
                      three_reg_not_r15),
         ThumbInstGen("111110101110nnnn1111dddd0000mmmm", // SSAX
                      three_reg_not_r15),
+        ThumbInstGen("111110101101nnnn1111dddd0000mmmm", // SSUB16
+                     three_reg_not_r15),
         ThumbInstGen("111110101001nnnn1111dddd0100mmmm", // UADD16
                      three_reg_not_r15),
         ThumbInstGen("111110101010nnnn1111dddd0100mmmm", // UASX
                      three_reg_not_r15),
         ThumbInstGen("111110101110nnnn1111dddd0100mmmm", // USAX
                      three_reg_not_r15),
+        ThumbInstGen("111110101101nnnn1111dddd0100mmmm", // USUB16
+                     three_reg_not_r15),
     };
 
     const auto instruction_select = [&]() -> u32 {